Carbetocin, CAS No: 37025-55-1, Pharmaceutical Peptide

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Solid
• Purity: >98%
• Model NO.: HJYY
• Characteristic: White Fluffy Powder
• Solubility: Soluble in Water, 1% Acetic Acid
• pH: 3.0-6.0
• Water: ≤6.0%
• Specific Rotation: -71º - -81º
• Assay: 95.0%-105.0%
• Transport Package: 1g/Al Bag
• Specification: 95.0%~99.0%
• Trademark: HD
• Origin: China
• HS Code: 2937190090
• Production Capacity: 100000g/Month

Product Description

   

Product Description

 Carbetocin, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a K_i of 7.1 nM. Carbetocin has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (K_i=1.17 μM). Carbetocin has the potential for postpartum hemorrhage research. Carbetocin can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS.

Detailed Photos

Product Parameters

 

Product Introduction
 

Generic name	Carbetocin
Formula	C45H69N11O12S
CAS No.	37025-55-1
Molecular Weight	988.17
EINECS	253-312-6

  Chemical Properties

Density	1.218±0.06 g/cm3(Predicted)
Melting Point	140 - 160°C
Boling Point	1477.9±65.0 °C(Predicted)
Solubility	Soluble in water, 1% acetic acid
Specific Rotation(α)	D -69.0° (c = 0.25 in 1M acetic acid)
Refractive Index	1.541
Storage Condition	-15°C
pka	13.07±0.70(Predicted)
Apperance	White to beige powder

Application & Efficacy

      After intravenous or intramuscular injection of carbetocin, the uterus contracts rapidly and can reach a definite strength within 2 minutes. The active effect of a single dose of intravenous carbetocin on the uterus can last about 1 hour, so it is sufficient to prevent postpartum hemorrhage just after birth. After giving carbetocin after delivery, the frequency and amplitude of contraction are longer than oxytocin.