Thymalfasin

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Solid
• HS Code: 2937190090
• Production Capacity: 100000g/Month

Product Description

    Thymalfasin (thymosin-α1) is an immunomodulatory agent that is able to augment some specific T lymphocyte functions, particularly that of promoting the T helper 1 cell responses involved in host antiviral defence. The most promising clinical applications for thymalfasin seem to be as a single agent for the treatment of chronic hepatitis B and in combination with interferon-α for the treatment of both chronic hepatitis B and C. These positive preliminary results offer a strong rationale for larger, well-planned clinical trials and also for defining the optimal schedule of administration.

Product Introduction
 

Generic name	Thymosin α1 /Thymosin Alpha-1
Synonyms	Thymalfasin, zadaxin, thymosin A1 bovine
Formula	C129H215N33O55
CAS No.	62304-98-7
Molecular Weight	3108.37
EINECS	1592732-453-0

  Chemical Properties

Density	1.360±0.06 g/cm3(Predicted)
Boling Point	2899.7±65.0 °C(Predicted)
Solubility	It is recommended to reconstitute the lyophilized Thymosin a1 in sterile 18MΩ-cm H2O not   less than 100 μg/ml, which can then be further diluted to other aqueous solutions.
Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Storage Condition	−20°C

Application & Efficacy

1. For the treatment of chronic hepatitis B.

2. A vaccine immune response enhancer as an immunocompromised patient. Immune system function is inhibited, including chronic hemodialysis and elderly patients, this product can enhance the immune response of patients with viral vaccines, such as influenza vaccine or hepatitis B vaccine.

A number of in vitro tests showed that the goods through the stimulation of peripheral blood lymphocytes promoting T lymphocyte mitogen original maturity, increase antigen or mitogen-activated T cells secrete interferon-α, interferon-γ and interleukin-2, interleukin-3, etc. lymphokines level, while increasing the T cell surface receptor level lymphokines. This product can also through the activation of CD4 cells, enhancing human allogeneic and autologous mixed lymphocyte reaction. It can be used to increase NK cells before aggregation, and enhanced cytotoxicity interferon can make it. In vivo tests showed that product can increase by Con A activated lymphocytes in mice interleukin-2 receptor expression levels, while increasing the secretion of interleukin-2 levels.