Cosmetic Ingredients Peptide Copper Peptide Ghk-Cu

• CAS No.: 49557-75-7
• Formula: C14h24n6o4
• EINECS: 1592732-453-0
• Type: Synthesis Material Intermediates
• Appearance: Powder
• Colour: Blue
• Origin: China
• Production Capacity: 10000000/G

Product Description

   Copper tripeptide (GHK-Cu) is a tripeptide. During wound healing, copper tripeptide may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a natural modulator of multiple cllular pathways in skin regeneration.
    Serveral copper(II)-peptide complexes occur naturally. In human plasma, the level of GHK-Cu is about 200 ng/ml at age 20. By the age of 60, the level drops to 80ng/ml. In humans, GHK-Cu is proposed to promote wound healing, attraction of immune cells, antioxidant and anti-inflammatory effects, stimulation of collagen and glycosaminoglycan synthesis in skin fibroblasts and promotion of blood vessels growth. Recent studies revealed its ability to modulate expression of a large number of human genes, generally reversing gene expression to a healthier state. Synthetic GHK-Cu is used in cosmetics as a reparative and anti- aging ingredient.

Product Introduction

Genertic name	Copper peptide GHK-Cu
Synonyms	Glycyl-L-Histidyl-L-Lysine; Growth-modulating peptide; Kollaren; Liver cell growth factor; Liver   growth factor Cu-GHK; Glycyl-histidyl-lysine, monocopper salt
CAS No.	49557-75-7
EINECS	1592732-453-0
Molar Mass	340.38
Density	1.324
Melting Point	>144ºC (dec.)
Boling Point	831.0±65.0ºC(Predicted)
Flash Point	456.4ºC
Solubility	Aqueous Acid (Slightly), DMSO (Slightly)
pKa	3.11±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8ºC

Application & Efficacy

    - Tighten loose skin and reverse thinning of aged skin
    - Repair protective skin barrier proteins
    - Improve skin firmness, elasticity, and clarity
    - Reduce fine lines, depth of wrinkles, and improve structure of aged skin
    - Smooth rough skin
    - Reduce photodamage, mottled hyperpigmentation, skin spots and lesions
    - Improve overall skin appearance
    - Stimulate wound healing
    - Protect skin cells from UV radiation
    - Reduce inflammation and free radical damage
    - Increase hair growth and thickness, enlarge hair follicle size