Powder: | Yes |
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Customized: | Customized |
Certification: | GMP, HSE, ISO 9001, USP, BP |
Suitable for: | Adult |
State: | Solid |
Purity: | >99% |
Customization: |
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Lanreotide (BIM 23014) is a somatostatin analogue with antineoplastic activity. Lanreotide can be used for the research of carcinoid syndrome.
Lanreotide is a synthetic cyclic octapeptide analogue of somatosyatin. Lanreotide binds to somatosyatin receptors (SSTR), specifically SSTR-2 and also to SSTR-5 with a lesser affinity. However, compare with octreotide, this agent is less potent in inhibiting the release of growth hormone from the pituitary gland. Furthermore, lanreotide has an acute effect on decreasing circulating total and free insulin-like growth factor 1 (IGF-I). This agent is usually given as a prolonged-release microparticle or Autogel formulation for the treatment of acromegaly and to relieve the symptoms of neuroendocrine tumors.
Lanreotide is a synthetic polypeptide analogue of somatosyatin that resembles the native hormone in its ability to suppress levels and activity of growth hormone, insulin, glucagon and many other gastrointestinal peptides. Because its half-life is longer than somatosyatin, lanreotide can be used clinically to treat neuroendocrine tumors that secrete excessive amounts of growth hormone (acromegaly) or other active hormones or neuropeptides. Lanreotide has many side effects including suppression of gall bladder contractility and bile production, and maintenance therapy may cause cholelithiasis and pancreatitis as well accompanying liver injury
Generic name | Lanreotide acetate |
Synonyms | IPSTYL, AUTOGEL, BIM-23014, LANREOTIDE, Lanreotide, ANGIOPEPTIN, H-D-2-NAL-CYS-TYR- D-TRP-LYS-VAL-CYS-THR-NH2, BETA-(2-NAPHTHYL)-D-ALA-CYS-TYR-D-TRP-LYS-VAL-CYS- THR AMIDE, H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-THR-NH2 (DISULFIDE BOND) |
Formula | C54H69N11O10S2 |
CAS No. | 108736-35-2 |
Molecular Weight | 1096.32 |
EINECS | 689-178-4 |
Density | 1.40±0.1 g/cm3(Predicted) |
Boling Point | 1508.2±65.0 °C(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
pka | 9.90±0.15(Predicted) |
Apperance | White or off-white powder |
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